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[Licence| Download | New Version Template] acfh_v1_0.gz(9 Kbytes)
Manuscript Title: Determination of antigenic determinants.
Authors: S. Fraga
Program title: DIAD
Catalogue identifier: ACFH_v1_0
Distribution format: gz
Journal reference: Comput. Phys. Commun. 30(1983)325
Programming language: Fortran.
Computer: AMDAHL 580/5860.
Operating system: MTS.
RAM: 10K words
Word size: 32
Peripherals: disc.
Keywords: Molecular, Proteins, Antigenic determinants, Vaccines, Structure, Biology.
Classification: 3, 16.1.

Nature of problem:
Determination of the sequence positions of the probable antigenic determinants in a protein.

Solution method:
The prediction of the sequence positions of the antigenic determinants is based on the characteristics of the hydrophilicity and recognition profiles of the protein under study.

Restrictions:
Only proteins involving the animo acids ala, arg, asn, asp, cys, glu, gln, gly, his, ile, leu, lys, met, phe, pro, ser, thr, trp, tyr and val (as well as hydroproline) may be studied. The animo acid sequence of the protein must be known.

Unusual features:
This program has been prepared from a version, in operation at the University of Alberta, which produces the graphical representations of the hydrophilicity, recognition and composite profiles for the protein under study. The plotting subroutines, available at the institution where the program will be run, may be used for this purpose.

Running time:
0.1 s for the test run (with three cases).